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Blood routine examination and biochemical parameters Fresh blood was collected by cardiac puncture when termination at postoperative 28 days

Guidelines from the British Committee for Standards in Hematology suggested the use of total serum vitamin B 12 as the first-line test, with MMA as the second-line test (Devalia et al., 12 does not reflect cellular, genetic, and pharmacological disturbances that lead to functional vitamin B 12 deficiency

Choline can be generated from phosphatidylcholine via phospholipases or converted to phosphatidylcholine via the cytidine diphospho-choline pathway (see Figure 2a)

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