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Malate generated in the TCA cycle can be converted to nicotinamide adenine dinucleotide phosphate (NADPH) under the catalysis of the malic enzyme (Son et al., 2013

The production of p-cresol sulfate and indoxyl sulfate in vegetarians versus omnivores

The structure of human ME2 in its binary complex with the cofactor NAD + is representative of open form I, whereas the structure of pentary complexes such as ME2-nucleotide (NAD + , NADH or ATP)-divalent cation (Mg 2+ or Mn 2+ )-substrate (pyruvate or L-malate)-fumarate is representative of closed form II of the enzyme 10,11,43

Enteric coating of HPMC capsules: HPMC capsules were coated with the Eudragit aqueous dispersion using a Glatt GC1 lab coater to a weight gain of 30%, 50% and 63% (calculated based on weight of empty capsules)