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320 Additionally, targeting a novel inducible GPX4 isoform could also mitigate ferroptosis and may be used to treat metabolic-associated fatty liver diseases

Our group previously reported on the modification of exocyclic amines of nucleobases with activated furan (keto-enal) 32,33

Omaveloxolone: an activator of Nrf2 for the treatment of Friedreich ataxia

Lower oxidative hemolysis was accompanied by higher levels of GSH in AS-3 RBC, faster glycolysis, higher ATP and DPG, higher PPP, decreased purine oxidation and protein damage- repair pathway activity (SAH) in AS-3 RBC independently of storage duration ( Online Supplementary Figure S4DE )