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The secoiridoid part is characterized by an open-ring configuration, which plays a pivotal role in its distinct chemical and biological behaviors

Meanwhile, rhubarb anthraquinones treatment enhanced intestinal immunity by modulating Treg/Th17 balance (Xiong et al

doi: 10.1038/s41366-020-0615-6 125 FjeldborgKChristiansenTBennetzenMJ MllerHPedersenSBRichelsenB

The putative role of oxidative stress and inflammation in the pathophysiology of sleep dysfunction across neuropsychiatric disorders: focus on chronic fatigue syndrome, bipolar disorder and multiple sclerosis