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The detoxification reactions comprise the first four steps of mercapturic acid synthesis, [19] with the conjugation to GSH serving to make the substrates more soluble and allowing them to be removed from the cell by transporters such as multidrug resistance-associated protein 1 (MRP1)

M., Stefan, H

To further support the potential of CJC-1295 (no DAC), the peptide bears four modifications, which, according to researchers such as Jette et al., involve the amino acids at positions 2, 8, 15, and 27

This is key since, unlike other cell types of the inner ear, HC in mammalians cannot be substantially replaced [37], which leads to persistent defects of auditory function