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We hypothesize that both the redox stress caused by GSH succination and Keap1 succination contribute to the emergence of the antioxidant signature and Nrf2 activation to support GSH biosynthesis and to maintain a viable level of oxidative stress

At the same time, two oral drugs, Deferiprone (DFP) and Deferasirox (DFX) , have been developed to address the short half-life of DFO , but side effects such as granulocyte deficiency (Lecornec et al., 2022)and renal failure (Kattamis, 2019)are still present during treatment

10.1038/ncb3064 9 AngeliJ

In dermatology and aesthetics research, GHK-Cu is most commonly associated with improving skin quality including support for collagen and elastin production , smoother-looking texture, and stronger skin-barrier structure