In the case of semax, a peptide that the nominators said could treat migraines, nerve pain in the face and a serious condition called cerebral ischemia, where there is not enough blood flow to the brain, the FDA scientists found insufficient evidence to recommend it
Heres our decision framework: Choose NAD+ IV if: You need fast, noticeable results for severe fatigue or brain fog You can block 23 hours once a month or quarterly at our Lincoln Park or Logan Square locations You want the highest bioavailability and physician supervision Youre doing an intensive longevity or anti-aging protocol Choose NAD+ Injections if: You want consistent NAD+ levels without the time commitment Youre comfortable with self-administration (we provide training) You travel frequently or have an unpredictable schedule Youre already doing peptide therapy or GLP-1 injections Choose NAD+ Nasal Spray if: You want to try NAD+ with minimal commitment Youre extremely time-constrained and need convenience Youre using it as maintenance after an IV or injection series Youre needle-averse and want the easiest entry point Real Patient Experiences in Chicago Im a corporate attorney and was hitting a wall every afternoon brain fog, no energy, relying on coffee that wasnt working anymore
Reported side effects are generally mild and include temporary gastrointestinal discomfort, headaches during initial use, occasional fatigue as the body adjusts, and rare nausea, especially when taken without food
A comment letter was submitted to the HOP Panel in advance of the August 25, 2025 HOP Panel Meeting that provided information about CPT codes 77407 and 77412
