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You would take psoralen by mouth or as an ointment, then get light therapy using UVA light

GH secretagogues begin amplifying growth hormone pulses, but the downstream effects on fat metabolism take time to accumulate

Any diet limiting intake to 500 calories daily will produce quick results, but such extreme restriction typically leads to muscle loss, nutritional deficiencies, and metabolic slowdown

Although the pramlintide/metreleptin combination seemed to be the next promising anti-obesity drug to be marketed, the sponsors discontinued its development in 2011, following commercial reassessment of the program (26)