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Reactions were performed with 0.001 mg/ml DNA substrate Poly(dI-dC), 1 M radiolabelled S-adenosyl-L-[methyl-3H] methionine (SAM) co-substrate, and recombinant human DNMT1 enzyme

Although inflammation is a cornerstone of asthma [49], several studies have shown that the nervous system plays a fundamental role in its pathogenesis [50,51,52,53]