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In rat with the treatment of 10 g/Kg/day BPC 157, the concentration of BPC 157 was estimated to be less than 1 g/ml in the blood which was too low to cause hypotension or hemodynamic change as demonstrated by the lack of vasodilation in the present study 6

Simulation studies indicate that once-daily co-administration of the present capsule achieves circadian hormone profiles closer to endogenous patterns than split or staggered schedules, supporting its use as a convenient, single-dose regimen