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The vast majority of the articles were focused on treatments of the disease, with surgery being the predominant topic

PLoS ONE 14 , e0213791 (2019)

In many studies looking at the efficacy of surgical treatment options for PD there is a lack of validated patient-reported outcomes looking at things such as the psychological impact of treatment, this partly explains why the American Urological Association guidelines for the treatment of PD rate the evidence basis for surgical treatment poorly [1]

Nonetheless, further longitudinal studies of antioxidant treatment in larger cohorts of biomarker selected patients, controlled by target engagement, are required