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Description

According to NICE guidance, hydroxocobalamin injections are the recommended first-line treatment for pernicious anaemia and other malabsorption-related deficiencies

Main Research Findings 1) Intra-articular administration of AOD9604 was shown to improve cartilage regeneration in cases of collagenase-induced knee osteoarthritis

NNMT is an enzyme that catalyzes the transfer of a methyl group from S-adenosylmethionine (SAM) to nicotinamide (NAM), producing 1-methylnicotinamide (MNA) and S-adenosylhomocysteine (SAH)

Moreover, pharmacokinetic evaluations reveal that AOD 9604 has a short plasma half-life of about three to four minutes intravenously and slower absorption when administered orally