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For toxicokinetic analysis of rat and monkey data, each animal was analyzed separately and results for each dose group were summarized as mean value and no formal statistical analysis was performed to determine the significance of the difference among the exposure groups

There are several major enzyme families involved in Phase I metabolism, including: Cytochrome P450 (CYP) enzymes : This is the most prominent family of enzymes involved in Phase I metabolism

Kv R, Liu TI, Lu IL, Liu CC, Chen HH, Lu TY, Chiang WH, Chiu HC

This procedure is a form of intravenous therapy that involves the administration of glutathione, a powerful antioxidant naturally found in the body