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Graphical Abstract Keywords: Ulcerative colitis, Pathophysiology, Plant extracts, Essential oils, Nutraceuticals, Phytocompounds Introduction Globally, the prevalence of ulcerative colitis (UC) has seen a significant rise, particularly in Northern Europe and North America, with two distinct age peaksone between 30 to 40 years and the other occurring in the 5th to 8th decades of life