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In the duodenum, pancreatic enzymes degrade the R-protein-B12 complexes, freeing B12 to bind with intrinsic factor (IF) , a glycoprotein produced by gastric parietal cells in the stomach lining

In this regard, increased loss of glutathione may change the intracellular environment to a prooxidant state and thereby caused prominent changes in gene expression, which is ultimately evolving into a malignant state [26]

[DOI] [PubMed] [Google Scholar] 43.Al-Batayneh K.M., Zoubi M.S.A., Shehab M., Al-Trad B., Bodoor K., Khateeb W.A., Aljabali A.A.A., Hamad M.A., Eaton G