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In: Handbook on the Toxicology of Metals

Graded-three-dimensional cell-encapsulating hydrogel as a potential biologic scaffold for disc tissue engineering

Vasc Pharmacol (2022) 142:106950

The oil-in-water method is suitable for water-soluble drugs, involving the dissolution of drugs and organic materials in the oil phase, followed by conversion to an aqueous phase through emulsification or ultrasound, resulting in the formation of nanoparticles with good dispersibility and stability 119