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Using CRISPR-Cas9 in human and mouse cells, genome-wide, targeted loss-of-function pooled screens have been studied that has provided information about the inactivated genomic loci and strategies that modulate transcriptional activities (Shalem et al., 2015)

Probiotic Clostridium butyricum ameliorated motor deficits in a mouse model of Parkinson's disease via gut microbiota-GLP-1 pathway

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788 Ubiquitin-specific protease 11 (USP11) is significantly upregulated in the spinal cord of mice with I/R injury and neuronal cells after hypoxia-reoxygenation