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doi:10.1097/j.pain.0000000000002500

By the fourth day of training, considered to be a crucial day on which the most improvement in training and neural plasticity occurs (Meighan et al., 2006), the scopolamine group (mean latency to find the pedestal=102.4 s) and the scopolamine+HingeDihexa group (mean latency=105.2 s) showed no signs of improvement compared to the vehicle control group (mean latency=43.0 s), the Hinge group (mean latency=78.3 s) and the scopolamineDihexa group (mean latency=63.0 s)

doi:10.1210/jc.2012-4262 Jones ML, Martoni CJ, Parent M, Prakash S

In animal-based models of depressive-like behavior, administration of the peptide was linked to attenuation of behavioral symptoms, indicating possible antidepressant-like activity under experimental conditions (25,26)