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For instance, SOD is known to be inactivated by increased hydrogen peroxide concentration, although its activity may also be reduced by glycosylation of the enzyme and/or loss of copper, an essential cofactor

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Methods Cell lines, cell culture, xenograft lines, animals, and animal protocols LNCaP, LAPC4 and VCaP cells were purchased from the American Type Culture Collection (ATCC) and cultured in RPMI-1640 medium (for LNCaP) or DMEM (for LAPC4 and VCaP) plus 10% heat-inactivated fetal bovine serum (FBS) and antibiotics

Rodney Twells, Andrew Sikorovsky, and Joseph Schmidt, according to a The move comes as the "My team and I believe that the client-advisor relationship is sacrosanct," Twells said in an interview