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23 In addition, for many decades increased immunostaining with antibodies against glial fibrillary acidic protein (GFAP) has been regarded as a universal molecular marker of astrocyte reactivity

Norisoboldine Norisoboldine (NOR), the main isoquinoline alkaloid present in the dried roots of Radix Linderae, may have certain anti-RA activity (70, 71), which can improve synovitis and abnormal immune status of CIA mice, and inhibit the activation of RAW264.7 macrophages by down-regulating the MAPKs signaling pathway