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In this sense, MOTS-c works as an endogenous exercise mimetic, triggering AMPK activation through the same molecular lever that exercise pulls, just from the inside [1]

Secreted protein was purified from supernatant using CaptureSelect Human albumin affinity matrix (ThermoFisher, #191297005) by elution with 2 M MgCl 2 , pH 7.4

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[2] Injectable dexamethasone appears on the World Health Organization Model List of Essential Medicines and is considered a standard of care for cerebral edema, acute asthma exacerbations, spinal cord compression, and adrenal crisis