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This is the same absorption pathway exploited by sublingual cardiac medications, hormone therapies, and other compounds where high bioavailability and speed of absorption matter

The evidence is strong enough that many psychiatrists consider escitalopram a reasonable first-line off-label option for social anxiety disorder

91 A number of studies, including the detection of brain metabolism abnormalities and hyperlactacidemia, demonstrated a disturbance in brain energy metabolism in autistic patients, which may be a result of mitochondrial oxidative phosphorylation dysfunction in neuronal cells