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Anti-inflammatory Effects: It can reduce liver inflammation, which is critical for conditions like non-alcoholic fatty liver disease (NAFLD)

Unlike the de novo synthesis of FA, FA transport is more prominent in animal models in vivo, especially the uptake and transport of long-chain FA, which partially explains the insignificant anticancer effect of FASN inhibitors in vivo [221]

NO activates soluble guanylate cyclase [174], resulting in the generation of cGMP, which in turn activates cGKI [175]

Like taxanes, vinca alkaloids (vincristine, vinblastine) are anti-mitotic agents that target microtubules, however, these inhibit polymerization (57)