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Recent research has highlighted the potential for microbiome-based therapeutic strategies, such as probiotics, prebiotics, fecal microbiota transplantation (FMT), and dietary modifications, to restore microbial balance and alleviate disease symptoms

Glutamate-mediated neurotoxicity has been dubbed as excitotoxicity, referring to the consequence of the overactivation of the N -methyl D-aspartate (NMDA)type glutamate receptors, leading to increased Na + and Ca 2+ influx into neurons (Choi, 1992