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FDA also identified potential immunogenicity concerns associated with peptide aggregation and related impurities

Carbohydr Polym 331:121860 Jha K, Doshi A, Patel P, Shah M (2019) A comprehensive review on automation in agriculture using artificial intelligence

Compared to its sister vaccine VBI-2902, which only contains the ancestral Wuhan-Hu-1 spike, VBI-2901 generated a 2.5-fold stronger response to the ancestral strain and a ninefold stronger response against the bat coronavirus [148]

However, as it was necessary to estimate a unique model parameter set for each individual in order to infer the glucose curve, this method is computationally much more heavy than cubic splining