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3A), which is heavily glycosylated with sugars comprising over 30% of the total mass of the proIGF-1Ea (Fig

Scientists isolated a portion of a larger protective protein in stomach secretions and synthesized a stable version for research purposes

Defective intrinsic factor synthesis arises from mutations in the GIF (gastric intrinsic factor) gene and usually presents during infancy, after vitamin B12 stores are depleted (35)

This review discusses the stromal/cancer cell relationship, by using examples to illustrate a number of different ways in which cancer cells can rely on and contribute to their microenvironment both as a stable network and in response to therapy