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Wegener et al., 2015)

Additionally, leflunomide, an FDA-approved drug for arthritis, has been shown to inhibit the growth of PDAC tumors by inducing MFN2 expression and subsequent mitophagy [92]

This effect can often be offset by supplementing with iodine

GFR matures rapidly but variably over the first weeks to months of life, approaching adult values by one to 2 years of age ( Infants aged 112 months remain at elevated risk relative to older children