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Rising levels of NAPQI in the liver cause widespread damage, including lipid peroxidation, inactivation of cellular proteins, and disruption of DNA metabolism (Bessems 2001)

J Clin Immunol (2004) 24:54252

In contrast, the study performed on human prostate cancer (PC) cells demonstrated that the knockdown of SET7/9 attenuated the expression of Nrf2 antioxidant targets - Nqo1 and glutathione S-transferase theta 2 (Gstt2) expression in response to H 2 O 2 treatment

J Food Compos Anal 75:4960 Bremnes RM, Al-Shibli K, Donnem T et al (2011) The role of tumor-infiltrating immune cells and chronic inflammation at the tumor site on cancer development, progression, and prognosis: emphasis on non-small cell lung cancer