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Description

Psychiatry 87 , 144148 (2016)

44 Oxidative protein folding within the ER is facilitated by oxidoreductases such as protein disulfide isomerases (PDIs), ERp72, and ERp57, with PDI catalyzing thiol-disulfide exchange reactions to form native disulfide bonds in proteins

Additionally, VMP1-dependent selective mitophagy and mitochondrial fragmentation, driven by mtDNA, act as protective cellular mechanisms in pancreatitis, highlighting mtDNAs involvement in cellular responses to the disease (147)