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GSH scavenges free radicals and reactive oxygen species (ROS), protecting cells from damage caused by oxidative stress

Schimmer AD, Eh E, Borthakur G, Carter B, Schiller GJ, Tallman MS, Altman JK, Karp JE, Kassis J, Jacob C, Morris S, Jolvet J, Andreeff M

To conclude, we report for the first time that male mice that age in the absence of system x c have an extended lifespan, have reduced priming of the peripheral immune system and are protected against age-related decline in hippocampal function and memory, a feature of aging with a devastating impact on the elder

However, the role of diet in modifying disease progression in PSC and associated IBD remains underexplored