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There was no significant difference in liver MDA across groups, but groups F1 and F3 had significantly lower serum MDA than group F0

Over the past few years, we have seen the vital roles the metal nanomedicines play in the GSH-responsive and -exhausting strategies, and inorganic nanomaterials, MOFs, and platinum-based nanomaterials-mediated GSH depletion is expected to realize more powerful synergistic therapy based on rational design