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Description

Reexamination of the role of interplay between glutathione and protein disulfide isomerase

*Correspondence: Xiang-An Li, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Results Effect of MDR ABC transporters on the toxicity of anticancer chelator ligands We studied the toxicity of various chelators in the presence of 2 M Cu(II) or 10 M Fe(II) ions against A431 cells and their multidrug-resistant derivatives overexpressing ABCB1, ABCG2, or ABCC1