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The use of 3 H-Hinge to probe the interaction was based on the ability of 3 H-Hinge to bind specifically and with high affinity to HGF (Kawas et al., 2011)

10.1523/JNEUROSCI.1432-18.2018 220

Considering this, CVB infection, particularly persistent infection, may contribute to the overall demise of the cell population by further activating autoreactive T cells, augmenting the effects of autoimmunity, and by further inducing cell stress and death