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CCAT1 lncRNA Promotes Inflammatory Bowel Disease Malignancy by Destroying Intestinal Barrier via Downregulating miR-185-3p

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Increased metabolic rate and ATP consumption trigger mitochondrial dysfunction, consequently leading to reactive oxygen species (ROS) over-production (Tamaki et al., 2014), which is the basis of increased oxidative stress, even in the early stage of CKD

(3) Regulation of gut microbiota by RIOS Different types of oligosaccharides exert targeted regulation on gut microbiota: Fructooligosaccharides: promote the increased abundance of Bifidobacterium, Lactobacillus, Faecalibacterium, Ruminococcus, Sutterella , and Oscillospira (118)