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In conclusion, although the safety profile of probiotics is well established for the healthy majority, caution is warranted in certain vulnerable populations

Protein binding Clozapine displaces warfarin and digoxin from proteins leading to increased exposure of both drugs Additive Adverse Effects There is a risk of myelosuppression if clozapine is administered alongside other drugs that can cause myelosuppression, such as long acting depot antipsychotics or carbamazepine

doi: 10.1371/journal.ppat.1007390 209 OnofrioL.CaragliaM.FacchiniG.MargheritaV.De PlacidoS.BuonerbaC

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