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We sought public comment on seven applications and make final determinations on these applications in this final rule with comment period

Methods Patients This study was approved by the institutional review board of all included hospitals, and informed consent from each patient was obtained

A case-control study (50 domestic shorthair cats with a confirmed diagnosis of FISS and 100 disease-free matched controls) investigating a possible association between polymorphisms in the genomic sequence of the feline p53 gene and a predisposition to FISS, found a strong association between FISS and the presence of specific nucleotides at two of the polymorphic sites (Banerji et al., 2007)