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In contrast, FINO2 both indirectly inhibits the enzyme function of GPX4 and directly oxidizes iron, ultimately leading to extensive lipid peroxidation [186, 187]

PMID: 324 WangT.ZhangN.YuX

Moreover, the numbers of pro-inflammatory murine Ly6C high monocytes were higher in mice fed a choline-rich diet which increased TMAO synthesis than in chow-fed control mice (Haghikia et al., 2018)

So contrary to what is typically done with dogs, most feline patients are not held off food and feeding tubes may be placed in the course of the disease if the cat refuses to eat