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Laurell and Eriksson observed in 1963 that individuals with a hereditary deficiency of the serum protein alpha-1 antitrypsin, which inhibits a number of serine proteinases such as neutrophil elastase, are at increased risk of developing emphysema 62

The glutathionylation or oxidation of roGFP2 was investigated by mixing reduced roGFP2 C151S or roGFP2 C208S with mmPEG in the presence of 5 mM GSSG or Diamide

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