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Cancer 10 , e003779 (2022)

For example, T lymphocytes upregulates the expression of guanylate-binding protein 1 in BC cells to facilitate the BBB transmigration

Moreover, glutamine can be targeted therapeutically, as demonstrated by its ability to repolarize macrophages from an M1 to an M2 phenotype, which can prevent obesity- or diabetes-associated pathology (Ren et al., 2019)