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PSC activated by PDAC cells rewrite its metabolic profile as aerobic glycolysis, producing nutrients such as lactate and non-essential amino acids to fuel the tricarboxylic acid (TCA) cycle and oxidative phosphorylation (OXPHOS) within PDAC cells, a phenomenon known as the reverse Warburg effect 15

It is essential to clearly state the reason for the injection, including the patient's symptoms, diagnosis or clinical indication (e.g

Remarkably, in terms of long-term impacts, the mice that received MSCs continuously maintained a 60%80% conception rate over a second breeding cycle, whereas the group treated with EXOs relapsed into infertility during the same period (Park et al., 2023)

Folate Receptor Autoantibodies (FRAAs) may impede proper folate transport