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Clinical trials have shown that patients on Semaglutide can lose up to 15% of their body weight over 68 weeks, whereas Phentermine users typically see an average loss of 5-10% of body weight over a shorter period

However, adding substantial volume to the under eye area to treat hollowing does require filler treatment, or in some cases a silicone tear trough implant, but not grafted fat due to a high rate of complications when used under thin eyelid skin

There may also be minor irritation at the injection site,for example, redness, tenderness, or a brief burning sensation where the NAD+ solution is injected subcutaneously