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On the other hand, synthetic ingredients such as hydroquinone and retinoids are commonly found in chemical-based treatments

This region is conserved in STX7 through species but it is not present in other STX family members (Supplementary Figs

To achieve rapid gelation and controlled redox-triggered dissolution under physiological conditions, orthogonal coupling strategies notably thiolmaleimide and thioldisulfide exchange chemistries have been adopted

The complex nature of RA and the incomplete understanding of its pathogenesis contribute to the lack of specific therapeutic measures in clinical practice, with drug therapy remaining the primary approach to managing disease progression and increasing patients quality of life [20]