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Tubular epithelial cell HMGB1 promotes AKI-CKD transition by sensitizing cycling tubular cells to oxidative stress: a rationale for targeting HMGB1 during AKI recovery

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Endoplasmic reticulum stress/Ca(2+)-calmodulin-dependent protein kinase/signal transducer and activator of transcription 3 pathway plays a role in the regulation of cellular zinc deficiency in myocardial ischemia/reperfusion injury

While observational studies consistently link selenium deficiency to worse outcomes, randomized clinical trials have shown inconsistent results, especially concerning mortality reduction and ICU length of stay