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Regulatory variability : Some countries (e.g., parts of Asia or Latin America) still require full safety data collection, limiting global protocol harmonization

Compared to the A375SM monoculture, 165 genes were differentially expressed (|log 2 FC| 1) in response to co-culture with M1 macrophages

469 Magnetic nanoparticles loaded with camptothecin, TMZ, and indocyanine green have shown strong anti-GBM effects, as validated through imaging techniques