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doi: 10.1016/j.phrs.2020.104936 148 FodorAAPimentelMCheyWDLemboAGoldenPLIsraelRJet al

The adjuvant use dosages of Leukine in clinical trials are generally much smaller than dosages for indications in the FDA-approved labeling

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According to a 2017 study published in Toxicology In Vitro, supplementing with high concentrations of pyridoxine may cause vitamin B6 deficiency ( 21 )