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The effects of TGF- signaling in cell proliferation, 15,16 cell differentiation, 17,18 embryonic development, 19 wound healing, 20 immune regulation, 21,22 tissue fibrosis, 23,24 and tumor development 25,26 have been studied shortly after the discovery of the cytokine

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10.1016/0006-2952(67)90015-9 173 JoyntM