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The investigation of the mechanism of glutathione deficiency in the lungs children with asthma has shown that dysregulation of glutathione-related antioxidant defense occurs due to dysfunction of a transcription factor that stimulates gene expression of the enzymes related to the antioxidant defense and glutathione production in cells

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They found that sedentary mice treated with 5-amino-1MQ and mice that underwent vigorous exercise had significantly lower levels of muscle cell fats, suggesting improved muscle quality