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CMS will also use quality measures and other data across the model to monitor impact and protect against any unintended consequences in the care delivered to beneficiaries or any negative changes in healthcare access or costs. 8 Other AHEAD Changes According to CMSs frequently asked questions on the changes, in addition to the above, participating states will need to implement new transparency requirements and incorporate additional risk-related measures

Simpler workflow at a fixed 5:1 ratio (commonly 12.5 mg retatrutide + 2.5 mg cagrilintide)

CagriSema is meant to be combined with a calorie-reduced diet and increased physical activity

PMID 17086939