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However, GFP levels and the GFP:BFP fluorescence ratio showed a small but significant increase in response to CB5083, MLN7243 and MG132, indicating that FSP1 is relatively stable under basal conditions but a portion is degraded by the ubiquitinproteasome system (Fig

The three compounds ship as separate lyophilised vials, not as a combined preparation, and are despatched from the UK