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It improved colonic inflammation, suppressed the NOD-like receptor protein 3 (NLRP3) inflammasome, and increased short-chain fatty acid-producing bacterial genera, which collectively contributed to mucosal healing and immune regulation

While individuals with mild vitamin B 12 deficiency may not experience symptoms, blood homocysteine and/or MMA may be elevated (18)

Effect of subcutaneous injections of PYY1-36 and PYY3-36 on appetite, ad libitum energy intake, and plasma free fatty acid concentration in obese males

Consistent with this, the Gmmorf2a/b mutants significantly enhanced resistance to UF-1 (Supplementary Fig